May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Reviewing Electroretinograms in Syndromic Retinitis Pigmentosa
Author Affiliations & Notes
  • J.C. Fleischhauer
    Dept of Ophthalmology, University Hospital Zurich, Zurich, Switzerland
  • W.A. Njoh
    Dept of Ophthalmology, University Hospital Zurich, Zurich, Switzerland
  • G. Niemeyer
    Dept of Ophthalmology, University Hospital Zurich, Zurich, Switzerland
  • Footnotes
    Commercial Relationships  J.C. Fleischhauer, None; W.A. Njoh, None; G. Niemeyer, None.
  • Footnotes
    Support  Schiller Foundation Zurich
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 5097. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      J.C. Fleischhauer, W.A. Njoh, G. Niemeyer; Reviewing Electroretinograms in Syndromic Retinitis Pigmentosa . Invest. Ophthalmol. Vis. Sci. 2004;45(13):5097.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose: to review phenotype and extent of changes in Ganzfeld ERGs in patients with syndromic RP seen in our ERG center. Patients and methods:Charts of 82 consecutive patients that presented during the last 20 years with syndromic RP were reviewed. Clinical data were compared to changes in the ERG. Ganzfeld ERGs largely, and recently fully adhering to the ISCEV standards, comprised selective rod–driven, maximal dark–adapted mixed responses, and isolated cone–driven signals. We used Henkes contact lens electrodes and occasionally recorded ERGs under brief general anaesthesia (abbreviated protocol; ARVO 2003). Results: Table I: summary of ERG findings. 

Conclusion: Much like in isolated RP, the phenotypes of patients presenting with syndromic retinal degeneration varied widely and often failed to show marked degenerative ophthalmoscopic changes. The ERG abnormalities included a wide range of changes of b–wave attenuation and variable rod– compared to cone–involvement. The extent of visible retinal abnormalities did not always correspond to the ERG deterioration. ERG testing, a prerequisite for assessing objectively retinal function, was important in establishing the diagnosis of syndromic RP.

Keywords: retinal degenerations: hereditary • electrophysiology: clinical 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×