May 2004
Volume 45, Issue 13
ARVO Annual Meeting Abstract  |   May 2004
OCT and EOG abnormalities in families with X–linked Retinitis Pigmentosa
Author Affiliations & Notes
  • M.L. Livani
    Ophthalmology, University, Roma, Italy
  • E. Rispoli
    Ophthalmology, University, Roma, Italy
  • R.H. F. Mendonça
    Ophthalmology, University, Roma, Italy
  • C. Morini
    Ophthalmology, University, Roma, Italy
  • E.M. Vingolo
    Ophthalmology, University, Roma, Italy
  • Footnotes
    Commercial Relationships  M.L. Livani, None; E. Rispoli, None; R.H.F. Mendonça, None; C. Morini, None; E.M. Vingolo, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 5105. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      M.L. Livani, E. Rispoli, R.H. F. Mendonça, C. Morini, E.M. Vingolo; OCT and EOG abnormalities in families with X–linked Retinitis Pigmentosa . Invest. Ophthalmol. Vis. Sci. 2004;45(13):5105.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Abstract: : Purpose:To determine the correlations between morphological (optical coherence tomography – OCT) and electrophysiological (electro–oculogram EOG) alterations in families with X–linked retinitis pigmentosa. Methods:Sixteen members of 4 different families: 7 obligate carriers, 4 affected male homozygote and 5 not affected females, underwent ophthalmological completed exams including EOG and OCT. All the subjects are previously tested with genetic analysis. Results:The abnormalities in OCT were detected in all carriers and affected males contrasting with no alterations in not affected females. The EOG was flat in all affected males. Distinctly subnormal in 8 eyes of obligate carries. Normal in 2 eyes of obligate carriers and in all not affected females. In two obligate carriers, the EOG was not performed due to a nuclear cataract. The correlations between OCT and EOG alterations were statistically significant. Conclusions: The OCT and EOG demonstrated to be a very sensible methods to identified the minimal alterations in carriers of X–linked Retinitis Pigmentosa.

Keywords: retinal pigment epithelium • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retinal degenerations: hereditary 

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.