Abstract
Abstract: :
Purpose: To estimate the prevalence of syndromes associated to RP and establish the most frequent clinical features .To know if the characteristics of RP are different in these syndromes compared with non syndromatic RP. Methods:A retrospective, descriptive and longitudinal study included complete records of patients with RP were reviewed from 1997 to 2003 in the Asociacion Para Evitar la Ceguera in Mexico Results:From 1088 records of patients with RP we found 106 patients with syndromatic RP. We observed 53.8% were male and 46.2% female. The mean age was 22 years. Usher syndrome was the most frecuent 48 (45.2%), followed by 37 cases of Bardet–Biedl (34.9%), we also had 11 cases of Kearns–Sayre (10.3%), 9 of Alstrom (8.4%) and 1 case of Cockayne syndrome. Conclusions:The most frequent syndromes were Usher and Bardet–Biedl. The clinical features of RP in Usher, Bardet–Biedl and Alstrom syndromes were the same as non syndromatic RP. We did not find clinical characteristics of RP in patients with Kearns– Sayre syndrome, in some cases only subnormal electroretinogram. Cockayne Syndrome is an uncommon disease.
Keywords: retina • clinical (human) or epidemiologic studies: prevalence/incidence • retinitis