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K.K. Parsa, E. de Jaun, Jr.; Positioning and stability evaluation of the Neo Vista brachytherapy system . Invest. Ophthalmol. Vis. Sci. 2004;45(13):5137.
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Purpose:The NeoVista Brachytherapy system is a new instrument designed for treatment of choroidal neovascular membrane in diseases such as Age related macular degeneration. This instrument uses a subretinal approach to deliver localized radiation to the diseased area and thus limiting the amount of radiation exposure of non–diseased retina. This subretinal approach requires the instrument to be placed approximately 1.5 mm from the target area to deliver the prescribed dosage of radiation. Controlling the distance between the target area and the radiation source is critical for ensuring delivery of prescribed dose to the target area. The pupose of this experiment is to evaluate the positioning and stability of the NeoVista Brachytherapy system to ensure accurate delivery of prescribed radiation in a simulated environment. Methods:Using an eye model to simulate the operative environment, three retinal surgeons used the Neo Vista Brachytherapy system to perform three procedures each. The surgeons held the device in the treatment position for the duration of the treatment. Radiochromic film was used to evaluate the stability and positioning of the instrument. The results from all three surgeons were averaged to obtain the maximum and minimum mean dose rate within 2.5 mm circle (treatment area) on the radiochromic film. The results were compared to the baseline testing results normalized to the proposed treatment dose of 25Gy. Results:The maximum mean dose rate within 2.5 mm circle for all surgeons was 26.13 Gy. And the minimum mean dose rate within 2.5 mm circle for all surgeons was 18.89. The standard deviation was 2.21 and the standard deviation percent of 9.9%. Conclusions:Based on our experiment the Neo Vista Brachytherapy system positioning and stability is adequate enough to ensure accurate delivery of prescribed radiation in a simulated use environment.
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