May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Reproducibility of retinal nerve fiber layer measurements using a scanning laser polarimeter with variable corneal compensation
R.D. Fechtner; J.M. Liebmann; M. Fingeret; E. Buroff; P.J. Lama; S. Zafar; R. Ritch
Author Affiliations & Notes
  • R.D. Fechtner
    Institute of Ophthalmology and Visual Science, New Jersey Medical School – UMDNJ, Newark, NJ
  • J.M. Liebmann
    Manhattan Eye, Ear and Throat Hospital, New York, NY
    New York University, New York, NY
  • M. Fingeret
    Department of Optometry, Department of Vetrans Affairs, New York Harbor Health Care System, Brooklyn, NY
    State University of New York College of Optometry, New York, NY
  • E. Buroff
    Institute of Ophthalmology and Visual Science, New Jersey Medical School – UMDNJ, Newark, NJ
  • P.J. Lama
    Institute of Ophthalmology and Visual Science, New Jersey Medical School – UMDNJ, Newark, NJ
  • S. Zafar
    The New York Eye and Ear Infirmary, New York, NY
  • R. Ritch
    The New York Eye and Ear Infirmary, New York, NY
    Deparment of Ophthalmology, New York Medical College, Valhalla, NY
  • Footnotes
    Commercial Relationships  R.D. Fechtner, Laser Diagnostic Technologies, Inc. F; J.M. Liebmann, Laser Diagnostic Technologies, Inc. F; Carl Zeiss Meditec, Inc. F; Heidelberg Engineering, Inc. F; M. Fingeret, Laser Diagnostic Technologies, Inc. F; Carl Zeiss Meditec, Inc. F; Heidelberg Engineering, Inc. F; E. Buroff, None; P.J. Lama, None; S. Zafar, None; R. Ritch, Laser Diagnostic Technologies, Inc. F; Carl Zeiss Meditec, Inc. F; Heidelberg Engineering, Inc. F.
  • Footnotes
    Support  Research to Prevent Blindness
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 5505. doi:
  • Views
  • Share
  • Tools
    • Alerts
      User Alerts
      You are adding an alert for:
      Reproducibility of retinal nerve fiber layer measurements using a scanning laser polarimeter with variable corneal compensation
      You will receive an email whenever this article is corrected, updated, or cited in the literature. You can manage this and all other alerts in My Account
      The alert will be sent to:
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation
      Citation

      R.D. Fechtner, J.M. Liebmann, M. Fingeret, E. Buroff, P.J. Lama, S. Zafar, R. Ritch; Reproducibility of retinal nerve fiber layer measurements using a scanning laser polarimeter with variable corneal compensation . Invest. Ophthalmol. Vis. Sci. 2004;45(13):5505.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

      ×
    • Get Permissions
  • Supplements
Abstract

Abstract: : Purpose: To assess the reproducibility of RNFL measurements in normal and glaucomatous eyes using a scanning laser polarimeter incorporating individualized corneal compensation. Methods: Twenty–five eyes of glaucoma patients and 27 eyes of normal volunteer were imaged three times each to determine short–term reproducibility of RNFL measurements. Measurements were performed using a scanning laser polarimeter (SLP) incorporating individualized variable corneal compensation (GDx–VCCTM, Laser Diagnostic Technologies, Inc., San Diego, CA). The variable corneal compensation algorithm was applied prior to obtaining each image. The standard deviation for each pixel was calculated from the three scans and averaged over the entire eye to give a mean sd value per patient. Reproducibility was defined as average of the mean standard deviation of pixels (excluding the region of the optic nerve) for the entire field, and the coefficient of variation for the parameters generated by the GDX–VCC software. Results: The mean standard deviation of the thickness map was 3.6 ± 1.0 for normals and 4.2 ± 1.1 for the glaucoma patients. Conclusion: Reproducibility of pixels was similar for normal and glaucomatous eyes. Reproducibility of calculated parameters was somewhat better in normal than glaucomatous eyes.The reproducibility for SLP with variable corneal compensation exceeds that reported for SLP with fixed corneal compensation. Coefficients of Variation 

Image not available
View OriginalDownload Slide
Image not available
View OriginalDownload Slide

Keywords: imaging/image analysis: clinical • nerve fiber layer 
© 2004, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept