May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
How does viscocanalostomy work? A new concept to the mode of action using scanning electron microscopy
Author Affiliations & Notes
  • P.C. Ruokonen
    Ophthalmology, Univ Hosp Charite, Berlin, Germany
  • E. Robinson
    Ophthalmology, Univ Hosp Charite, Berlin, Germany
  • A. Sänger
    Ophthalmology, Univ Hosp Charite, Berlin, Germany
  • C. Hartmann
    Ophthalmology, Univ Hosp Charite, Berlin, Germany
  • M.R. Tetz
    Tagesklinik am Spreebogen, Berlin, Germany
  • Footnotes
    Commercial Relationships  P.C. Ruokonen, None; E. Robinson, None; A. Sänger, None; C. Hartmann, None; M.R. Tetz, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 5541. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      P.C. Ruokonen, E. Robinson, A. Sänger, C. Hartmann, M.R. Tetz; How does viscocanalostomy work? A new concept to the mode of action using scanning electron microscopy . Invest. Ophthalmol. Vis. Sci. 2004;45(13):5541.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose: Several studies have proven the efficacy of viscocanalostomy as a non–penetrating approach in glaucoma surgery. The mechanism responsible for the decrease in intraocular pressure has not been clarified in detail.Methods: From a pool of over 200 patients having undergone standardized viscocanalostomy performed by one surgeon 45 eyes were selected for this study. 20 eyes were defined as a long–term success, whereas in 25 eyes, a repeat operation was necessary. The resected deep scleral flap was investigated using scanning electron microscopy. Morphological findings were correlated with the clinical outcome. Results: In 40 scleral flaps (89%), tissue of Schlemm’s canal was found. Absence of Schlemm’s canal correlated with early postoperative failure (p<0.05). The amount of anterior trabecular meshwork correlated well with the long–term success (p<0.01). The number of septae in Schlemm’s canal showed a significant coherence to the incidence of postoperative hypotony (p<0.001), whereas there was no significant correlation to the success rate.Conclusions: Schlemm’s canal was precisely deroofed in most of the cases. A deep sclerectomy without resection of anterior meshwork seems to have a lower effect on reduction of IOP. A microperforation of the inner wall of Schlemm’s canal due to resection of septae leads to a higher risk of early postoperative hypotony, but has no influence on long–term results.

Keywords: microscopy: electron microscopy • outflow: trabecular meshwork • sclera 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×