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V. Gulati, M. Latina; Outcomes of Repeat Selective Laser Trabeculoplasty in Open Angle Glaucoma Cases on Medications . Invest. Ophthalmol. Vis. Sci. 2004;45(13):5582.
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Abstract: : Purpose: Selective laser trabeculoplasty is a potentially repeatable procedure because of lack of coagulative damage to trabecular meshwork associated with the IOP–lowering effect. Methods: The study is a retrospective analysis of 20 eyes of 20 open–angle glaucoma patients on topical IOP lowering medications that underwent repeat SLT. Initial SLT was done over 180 degrees and repeat SLT was performed over previously untreated 180 degrees of trabecular meshwork. The two trabeculoplasties were performed at least 6 months apart. A minimum of 6 months follow up following each procedure was required for inclusion in the study. Results: The average number of medications being used per eye at baseline before first SLT was 1.95 + 1.30. Baseline IOP before first SLT was 25.75 + 8.89 mmHg. It was reduced to 20.74 + 3.95 mmHg and 20.69 + 4.95 mmHg at 1 and 6 months respectively after first SLT. Baseline IOP before second SLT was 21.65 + 3.96 mmHg. It was reduced to 19.71 + 3.81 mmHg and 18.36 + 3.64 mmHg 1 month and 6 months after the procedure. No complications were seen after either administration of SLT. The response rates (IOP reduction > 3mmHg) to the first and second SLT were 70% and 60% respectively. Conclusions: Successive administrations of 180 degrees SLT, done at least 6 months apart, produced an additional 20% and 15% lowering of IOP in cases of open–angle glaucoma on topical medications. The two 180 degree treatments produced a total of 29% reduction in IOP by the end of 6 months after 2nd SLT. This also suggests that initial 360 degrees SLT treatment may provide better IOP lowering effect than 180 degrees treatment. View OriginalDownload SlideView OriginalDownload Slide
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