May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
1 year results of a randomized clinical trial comparing Selective Laser Trabeculoplasty (SLT) to Argon Laser Trabeculoplasty (ALT)
A.M. Bovell; K.F. Damji; W.G. Hodge; W. Rock; R. Buhrmann; Y.I. Pan
Author Affiliations & Notes
  • A.M. Bovell
    Ophthalmology, University of Ottawa Eye Institute, Ottawa, ON, Canada
  • K.F. Damji
    Ophthalmology, University of Ottawa Eye Institute, Ottawa, ON, Canada
  • W.G. Hodge
    Ophthalmology, University of Ottawa Eye Institute, Ottawa, ON, Canada
  • W. Rock
    Ophthalmology, University of Ottawa Eye Institute, Ottawa, ON, Canada
  • R. Buhrmann
    Ophthalmology, University of Ottawa Eye Institute, Ottawa, ON, Canada
  • Y.I. Pan
    Ophthalmology, University of Ottawa Eye Institute, Ottawa, ON, Canada
  • Footnotes
    Commercial Relationships  A.M. Bovell, None; K.F. Damji, None; W.G. Hodge, None; W. Rock, None; R. Buhrmann, None; Y.I. Pan, None.
  • Footnotes
    Support  Lumenis Inc.
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 5586. doi:
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      A.M. Bovell, K.F. Damji, W.G. Hodge, W. Rock, R. Buhrmann, Y.I. Pan; 1 year results of a randomized clinical trial comparing Selective Laser Trabeculoplasty (SLT) to Argon Laser Trabeculoplasty (ALT) . Invest. Ophthalmol. Vis. Sci. 2004;45(13):5586.

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Abstract

Abstract: : Purpose: SLT is a frequency doubled, q–switched, YAG laser that specifically targets melanin–laden trabecular meshwork cells, and is used to lower intraocular pressure (IOP) in open angle glaucoma. We conducted a randomized, controlled, clinical trial comparing the efficacy of SLT to ALT. Methods: 176 eyes with open angle glaucoma, on medical therapy, with some eyes that had undergone previous ALT treatment, were enrolled and randomized to undergo either SLT or ALT, using standard treatment parameters. 145 eyes had reached 1 year at the time of this analysis. Primary outcome was change in IOP from pretreatment baseline. Univariate and multivariate analyses were performed. Results: Baseline comparison was similar between SLT (n= 89) and ALT (n=87) groups including IOP (23.8mmHg +/– 4.9 and 23.5 mmHg +/– 4.2, respectively). 1 year IOP drops were very similar in the SLT (–6.0mmHg +/– 6.03, n=72) and ALT (–6.0mmHg +/– 4.85, n=73) groups. There was no statistically significant difference in IOP change between groups. There were an equal number of medication changes in each group. Conclusions: The IOP lowering effect of SLT is equivalent to ALT at 1 year in patients with established glaucoma. Acknowledgement: Lumenis Inc. provided financial support for this study

Keywords: laser • intraocular pressure • trabecular meshwork 
© 2004, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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