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M. Ayaki, S. Suzuki, T. Tsuchiya, T. Onishi, S. Yaguchi; Three Years Prospective Randomized Study of Glistening and Surface Light Scattering of Acrylic Intraocular Lens in Eyes Treated With Topical Diclofenac and Betamethasone . Invest. Ophthalmol. Vis. Sci. 2003;44(13):218.
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Purpose: To investigate glistening and surface light scattering of acrylic intraocular lens (IOL) in eyes treated with diclofenac sodium (DFNa) and betamethasone phosphate (BMS) ophthalmic solutions. Methods: A total of one hundred eyes with acrylic IOL (MA30BA, Alcon laboratories) implantation were randomly treated with either of topical agents for three months postoperatively. Thirty-one cases of DFNa group and 31 of BMS met the criteria after 3 years and the severity of glistening and anterior surface light scattering of central portion of IOLs was evaluated by Scheimpflug photography. Averaged age and number of diabetes mellitus cases were 73.8 y/o and five (16.1%) eyes in DFNa and 75.0 y/o and seven (22.2%) eyes in BMS. Cases with major intraoperative complications, inflammatory diseases or posterior capsulotomy were excluded. Results: Averaged measurements of anterior surface light scattering of IOLs were 24.0 CCT (computer compatible tapes) in DFNa group and 26.9 CCT in BMS group (p=0.081). Photographically detectable glistening was noted in 45.2%(14/31) of DFNa group and 19.4%(6/31) of BMS group (p=0.030). Conclusions: Development of glistening in acrylic IOL may be earlier in the eye treated with DFNa than with BMS, since glistening occurs in many of implanted acrylic IOLs after years.
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