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C.E. Jahn, M.A. Jahn, C.F. Kreiner, A. Serester, I. Fromberg, S. Jacobi, S. Deutschmann, E.H. Schäffer, B.A. Kamppeter; Investigation of an Intraocular Lens with Reversibly Adjustable Optical Power : *Acri.Tec AR-1 . Invest. Ophthalmol. Vis. Sci. 2003;44(13):262.
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Purpose: To examine if it is technically feasible and safe to implant and adjust an intraocular lens with reversibly adjustable refractive power designed to correct residual postoperative refractive error. Methods: Implantation of the *Acri.Tec AR-1 PC/IOL into pig cadaver eyes after removal of the lens through phacoemulsification. Manipulation of the lens in order to change the refractive power. Implantation of the *Acri.Tec AR-1 PC/IOL into eyes of rabbits after removal of the lens through phacoemulsification. Manipulation of the lens four weeks after implantation in order to change the refractive power. Results: Implantation and adjustment of refractive power was possible without any problem. The eyes healed normally. No difference between eyes containing the *Acri.Tec AR-1 PC/IOL and eyes containing the control IOL could be detected with respect to signs of inflammatory reaction, corneal transparency and histopathologic appearance. Conclusions: The *Acri.Tec AR-1 PC/IOL demonstrates that such an IOL can be implanted easily and that it is well tolerated in rabbit eyes. Surgical adjustment of the adjusting element can be performed with little effort several weeks after implantation. This IOL holds promise of correcting residual refractive error after cataract surgery.
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