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T. Kida, S. Harino, T. Nakagawa, A. Kubota, Y. Iwahashi; Changes in Blood Flow of Retinal Vein at the Arteriovenous Crossing Site in Hypertensive Patients . Invest. Ophthalmol. Vis. Sci. 2003;44(13):346.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: Branch retinal vein occlusion (BRVO) occurs typically at an arteriovenous crossing where the artery passes anterior to the vein and systemic hypertension is well known as one of the risk factors in BRVO. In the present study, we investigated changes of retinal venous blood flow at the surrounding site of arteriovenous crossing in hypertensive patients. Methods:Fourteen patients with systemic hypertension and fifteen healthy volunteers with no ocular disease other than mild refractive errors as a control were included. The blood velocity and vessel diameter of the retinal vein at both one disc diameter proximal and distal to the arteriovenous crossing site was measured by laser Doppler velocimetry with the eye-tracking system (Canon Laser Blood Flowmeter CLBF model 100, Canon Inc., Tokyo, Japan). Results: There were no significant changes at the site of crossing in retinal vein diameter between hypertensive patients and control. The blood velocity did not change at the proximal and distal site of crossing in control, whereas decreased significantly (17.0±15.7%) at the distal site in patients with hypertension (p=0.027). Blood flow tended to decrease at the distal site in hypertensive patients, but the change was not statistically significant. Conclusions: We found that the velocity of retinal vein decreased at the distal site of arteriovenous crossing in patients with normal fundus and systemic hypertension. At the site of crossing, vein blood flow may be impaired in patients with hypertension before BRVO is manifested clinically.
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