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A.D. Currie, Y. Wen, J. Koeppens, W. Kiel, C. Barber, S.A. Vernon, A.J. King; Correlation between Humphrey Visual Field ( HVF), Multifocal Electroretinogram ( mfERG ), Multifocal Visually Evoked Potentials ( mfVEP ) and Heidelburg Retinal Tomograph ( HRT ) Optic Disc Topography in Patients with Glaucoma . Invest. Ophthalmol. Vis. Sci. 2003;44(13):42.
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Purpose: To establish the extent of correlation between psychophysical visual field analysis (HVF), two methods of objective visual field assessment ( mfERG and mf VEP ) and objective analysis of optic disc changes ( HRT ) in patients with glaucoma. Methods: The left eye of 21 patients with glaucoma underwent 30-2 HVF sita standard, 60 degree mfERG and mfVEP and HRT disc topography. The Pearson Correlation was used for statistical analysis. Correlation between the HVF threshold sensitivity and N1, P1 and N2 latency and amplitudes for mf ERG and mf VEP were undertaken for upper nasal, lower nasal, upper temporal and lower temporal quadrants and superior, inferior, nasal and temporal hemifields. In addition correlation of these parameters with the parameters of HRT analysis were performed. A value of < 0.05 was considered significant. Results: There was no correlation between the HVF and mfERG for any comparisons. For quadrant analysis, there was significant correlation between HVF quadrant sensitivity and N1 latency and N1, P1 and N2 amplitudes in the upper temporal quadrant and amplitude of N1 and P1 in the upper nasal quadrant. For hemifield analysis, there was significant correlation between the latency of N1 and P1 and amplitude of N1 in the temporal hemifield and the amplitude of N1, P1 and N2 for the upper hemifield. HRT correlation was found between cup shape measure and both whole field mfERG and whole field mfVEP. Conclusion: Correlation between quadrant and hemifield analysis for mf VEP and HVF confirms the ability of the mfVEP to detect glaucomatous damage. Glaucoma has an effect on both the amplitude and latency of the components of the mfVEP. .
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