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S. Xu, D. Meyer, S. Yoser; Photodynamic Therapy for Choroidal Neovascularization in Ocular Histoplasmosis Syndrome . Invest. Ophthalmol. Vis. Sci. 2003;44(13):579.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To study the results of photodynamic therapy (PDT) with verteporfin for choroidal neovascularization (CNV) secondary to ocular histoplasmosis syndrome (OHS). Methods: Clinical medical records including fluorescein angiograms and color photos of 56 eyes (52 patients) were retrospectively studied. The mean follow-up time(FUT) was 11.25 (3 to 30) months. Visual acuity (VA), recurrence of CNV and complications were investigated. Visual acuity changes by more than 2 Snellen lines was defined as improved or decreased, changes within 2 lines were defined as stabilized. Results: The changes of VA in different follow-up periods were : Repeated PDT treatments occurred: 2nd PDT in 37eyes, 3rd PDT in 16 eyes, 4th PDT in 9 eyes, 5th PDT in 2 eyes, and one eye has been treated 9 times. CNV recurred in 3 eyes, in 9 (2 eyes) and 15 months after last treatment. No obvious complication was observed during or post PDT treatment. Conclusion: Photodynamic therapy with verteporfin for choroidal neovascularization in OHS is an effective therapy offering the possibility of maintaining central vision in 70% to 80% of eyes. Supported by Crippled Children Vitreoretinal Research Foundation View OriginalDownload SlideView OriginalDownload Slide
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