May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Long-Term Outcomes in Asians after Acute Angle-Closure
Author Affiliations & Notes
  • S.L. Seah
    Glaucoma, Singapore National Eye Center, Singapore, Singapore
  • T. Aung
    Glaucoma, Singapore National Eye Center, Singapore, Singapore
  • P.T. Chew
    Ophthalmology, National University of Singapore, Singapore, Singapore
  • G. Gazzard
    Ophthalmology, National University of Singapore, Singapore, Singapore
  • L.P. Ang
    Ophthalmology, National University of Singapore, Singapore, Singapore
  • Y. Lai
    Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, United States
  • L. Yip
    Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore
  • H. Lai
    Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore
  • H. Quigley
    Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore
  • D.S. Friedman
    Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore
  • Footnotes
    Commercial Relationships  S.L. Seah, None; T. Aung, None; P.T.K. Chew, None; G. Gazzard, None; L.P.K. Ang, None; Y. Lai, None; L. Yip, None; H. Lai, None; H. Quigley, None; D.S. Friedman, None.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 90. doi:
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    • Get Citation

      S.L. Seah, T. Aung, P.T. Chew, G. Gazzard, L.P. Ang, Y. Lai, L. Yip, H. Lai, H. Quigley, D.S. Friedman; Long-Term Outcomes in Asians after Acute Angle-Closure . Invest. Ophthalmol. Vis. Sci. 2003;44(13):90.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To determine the long-term outcome of eyes suffering an acute attack of angle-closure (AAC) and to identify risk factors at presentation associated with loss of visual function. Methods: All individuals suffering AAC two to nine years previously at two Singapore hospitals underwent a complete eye examination including visual acuity, visual field testing, dilated eye examination and optic nerve head photography. The optic discs were judged clinically as to whether there was glaucomatous optic neuropathy present, and visual fields assessed if there was glaucomatous visual field loss. All visual fields and optic nerve photographs underwent a second evaluation by an experienced but masked glaucoma specialist, who assessed if the changes were compatible with glaucoma. Blindness was defined as best corrected visual acuity which was worse than 6/60, and/or central visual field of less than 20 degrees in the study eye. Results: A total of 90 of 170 eligible subjects (65.2%) were examined. All subjects were Asian, and were predominantly Chinese (78 subjects-86.7%). There were 61 females (67.8%) and 29 males (32.2%). The mean age of subjects was 62.0 (SD 9.0) years at the time of the attack with a mean duration of 6.3 (SD 1.5) years from the time of the AAC episode to the study examination. Sixteen (17.8%) subjects were blind in the attack eye, half of the cases of blindness caused by glaucoma. Forty-three subjects (47.8%) had glaucoma with 13 eyes (15.5%) having markedly cupped optic discs (CDR > 0.9). Thirty-eight eyes (58%) had best-corrected vision < 6/9, with cataract responsible for close to half the cases of vision loss. There were no identifiable risk factors related to the AAC episode that was significant for outcome. Conclusions: Several years after presenting with AAC, 17.8% of subjects examined were blind in the attack eye, and almost half had glaucomatous optic nerve damage. Vision was also reduced in a large number of individuals, largely from un-operated cataract.

Keywords: clinical (human) or epidemiologic studies: nat • clinical (human) or epidemiologic studies: out • optic disc 
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