May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Ultrasound Biomicroscopy (UBM) of Ciliary Processes in Uveitis
Author Affiliations & Notes
  • E. Saavedra
    Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, OH, United States
  • D. Socci da Costa
    Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, OH, United States
  • L. Sculley
    Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, OH, United States
  • C.Y. Lowder
    Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, OH, United States
  • Footnotes
    Commercial Relationships  E. Saavedra, None; D. Socci da Costa, None; L. Sculley, None; C.Y. Lowder, None.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 695. doi:
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      E. Saavedra, D. Socci da Costa, L. Sculley, C.Y. Lowder; Ultrasound Biomicroscopy (UBM) of Ciliary Processes in Uveitis . Invest. Ophthalmol. Vis. Sci. 2003;44(13):695.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To determine the effect of duration, severity, and location of uveitis on the length of ciliary processes. Methods: Ultrasound biomicroscopy (UBM) of ciliary processes was obtained in superior, temporal, nasal, and inferior quadrants in 91 uveitic eyes and 16 normal eyes. The five longest ciliary processes measured in microns from each quadrant were analyzed with regards to duration (acute, chronic, and recurrent), severity (aggressive, moderate, and mild), and location (anterior, intermediate, posterior, and diffuse) of uveitis. Results: Ciliary processes measurements were as follows. Duration: inferior (chronic, 356.33; acute, 423.96; normal, 534.64; P = 0.004); nasal (chronic, 434.69; acute, 457.46; normal, 565.33; P = 0.017); temporal (chronic, 467.75; acute, 487.75; normal, 582.48; P = 0.015); and superior (chronic, 498.70; acute, 549.97; normal, 581.17; P = 0.127). Severity: inferior (aggressive, 334.38; moderate, 392.59; mild, 429.50; normal, 523.23; P = 0.007); nasal (aggressive, 413.79; moderate, 465.99; mild, 444.98; normal, 562.74; P = 0.018); temporal (aggressive, 429.52; moderate, 509.47; mild, 492.55; normal, 577.48; P = 0.007); and superior (aggressive, 480.44; moderate, 558.62; mild, 480.08; normal, 568.33; P = 0.146). Location: inferior (diffuse, 338.57; intermediate, 533.00; anterior, 421.18; normal, 530.81; P = 0.003), nasal (diffuse, 423.04; intermediate, 502.90; anterior, 464.67; normal, 565.47; P = 0.024), temporal (diffuse, 441.29; intermediate, 558.00; anterior, 516.77, normal, 584.99; P = 0.007), and superior (diffuse, 489.25; intermediate, 561.60; anterior, 545.46; normal, 578.05; P = 0.190). Conclusions: Significant differences in ciliary process lengths were found between eyes with and without uveitis. Greatest damage to ciliary processes were found in eyes with chronic, aggressive, and diffuse uveitis. Superior quadrant ciliary processes were least susceptible to damage. Information on ciliary processes may be used to guide management of patients with uveitis.

Keywords: ciliary body • imaging/image analysis: clinical • uveitis-clinical/animal model 
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