May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Validation of a Screening Rule for Thyroid Orbitopathy
K. Mohaseb; M. Linder; P. Dolman; G.E. Wilkins; J. Rootman
Author Affiliations & Notes
  • K. Mohaseb
    Ophthalmology, University of British Columbia, Eye Care Centre, Vancouver, BC, Canada
  • M. Linder
    Epidemiology, University of British Columbia, Vancouver, BC, Canada
  • P. Dolman
    Epidemiology, University of British Columbia, Vancouver, BC, Canada
  • G.E. Wilkins
    Medicine, Division of Endocrinology, University of British Columbia, Vancouver, BC, Canada
  • J. Rootman
    Medicine, Division of Endocrinology, University of British Columbia, Vancouver, BC, Canada
  • Footnotes
    Commercial Relationships  K. Mohaseb, None; M. Linder, None; P. Dolman, None; G.E.L. Wilkins, None; J. Rootman, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 768. doi:
  • Views
  • Share
  • Tools
    • Alerts
      User Alerts
      You are adding an alert for:
      Validation of a Screening Rule for Thyroid Orbitopathy
      You will receive an email whenever this article is corrected, updated, or cited in the literature. You can manage this and all other alerts in My Account
      The alert will be sent to:
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation
      Citation

      K. Mohaseb, M. Linder, P. Dolman, G.E. Wilkins, J. Rootman; Validation of a Screening Rule for Thyroid Orbitopathy . Invest. Ophthalmol. Vis. Sci. 2003;44(13):768.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

      ×
    • Get Permissions
  • Supplements
Abstract

Abstract: : Purpose: To validate a screening tool for the early identification of thyroid orbitopathy. Methods: The self-reporting symptomatology questionnaire called the Thyroid Orbitopathy Indicator was administered along with a standard ophthalmic examination to patients newly diagnosed with Grave's hyperthyroidism. The patients were initially diagnosed by endocrinologists and asked to take part in the study. The questionnaire and its resulting rule (Vancouver Orbitopathy Rule) were then compared to the ophthalmic examination to determine the efficacy of the screening rule in diagnosis of thyroid orbitopathy. Results: Through analysis of 49 patients, the Vancouver Orbitopathy Rule was found to have a sensitivity of 0.82 and specificity of 0.75. The instrument's positive predictive value was 0.64 and its negative predictive value was 0.89. Conclusions: The Vancouver Orbitopathy Rule is a useful screening tool in the early diagnosis of thyroid orbitopathy.

Keywords: clinical (human) or epidemiologic studies: tre • orbit • clinical research methodology 
© 2003, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept