May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Central Corneal Thickness in a Subgroup of the European Glaucoma Prevention Study
Author Affiliations & Notes
  • A.I. Vogel
    Ophthalmology, Johannes Gutenberg University, Mainz, Germany
  • I. Kersten-Gomez
    Ophthalmology, Johannes Gutenberg University, Mainz, Germany
  • R. Troost
    Coordination Center For Clinical Trials, Johannes Gutenberg University, Mainz, Germany
  • S. Pourjavan
    Ophthalmology, St. Rafaelkliniek, Leuven, Belgium
  • G. Bertoni
    Ophthalmology, Ospedale "L. Sacco", Milano, Italy
  • S. Gandolfi
    Ophthalmology, University of Parma, Parma, Italy
  • T. Zeyen
    Ophthalmology, Middelheim Hospital, Antwerpen, Belgium
  • S. Miglior
    Ophthalmology, University of Milano, Milano, Italy
  • N. Pfeiffer
    Ophthalmology, University of Milano, Milano, Italy
  • EGPS-Study Group
    Ophthalmology, University of Milano, Milano, Italy
  • Footnotes
    Commercial Relationships  A.I. Vogel, MSD F; I. Kersten-Gomez, MSD F; R. Troost, None; S. Pourjavan, MSD F; G. Bertoni, MSD F; S. Gandolfi, MSD F; T. Zeyen, MSD F; S. Miglior, MSD F; N. Pfeiffer, MSD F.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2171. doi:
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    • Get Citation

      A.I. Vogel, I. Kersten-Gomez, R. Troost, S. Pourjavan, G. Bertoni, S. Gandolfi, T. Zeyen, S. Miglior, N. Pfeiffer, EGPS-Study Group; Central Corneal Thickness in a Subgroup of the European Glaucoma Prevention Study . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2171.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: Central corneal thickness (cct) was reported to be increased in patients with ocular hypertension. The purpose of our study was to investigate the distribution of cct in a subgroup of ocular hypertensive patients within the European Glaucoma Prevention Study (EGPS). Methods: In a subgroup of 369 out of 1077 EGPS patients (mean age: 60±11years, 58% females, 42% males) cct was measured using ultrasonic pachymetry. 72% of the measurements were performed am and 28% pm, all of them were performed after visual field testing and tonometry. Correlations between central cct and age, gender and time of measurement were investigated. Results: Mean cct was 569±34µm for right eyes and 570±34µm for left eyes. 17.6% of the EGPS patients had a cct > 600µm. There was no correlation between cct and age (r=-0,012). Females had thinner corneas than males (568µm and 572µm, respectively, p= 0,039). And cct was found to be higher in the afternoon than in the morning (574µm and 567µm, respectively, p=0,002). Conclusions: Ocular hypertensive patients within the EGPS show increased cct. 17.6% of the EGPS patients had a cct > 600µm. Measurements in the afternoon showed thicker ccts than measurements in the morning. As our sample size represents only 1/3 of the whole EGPS sample, generalization should be avoided. Our results are in accordance with recent data from the Ocular Hypertension Treatment Study (Ophthalmology, 2001).

Keywords: intraocular pressure 
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