Abstract
Abstract: :
Purpose: To verify the reproducibility of the Water Drinking Test (WDT) in glaucomatous or glaucomatous suspect patients. Methods: Retrospective analysis of WDT data from 22 glaucomatous or glaucomatous suspect patients who had been submitted to the same test twice and performed by the same examiner at the same period of the day and with one to four weeks interval between each test. One eye of each patient was randomly selected for statistical analysis. Intraclass Correlation Coefficient (ICC) was used to assess the reproducibility of the WDT. According to the ICC values, this test could be classified as: Poor Reproducibility (ICC < 0.4), Satisfactory Reproducibility (0.4≤ICC < 0.75) or Excellent Reproducibility (ICC ≥0.75). Results: Mean age was 52.5±12.8 (32-79) years old. Mean IOP + dp values were: 14.6±3.1 mmHg (Before water ingestion - Basal IOP), 16.5±3.2 mmHg (15 minutes after water ingestion), 17±3.9 mmHg (30 minutes) and 16.5±4.03 mmHg (45 minutes). Retest values were: 13.4±3.2 mmHg (Basal IOP), 15.8±3.2 mmHg (15 minutes), 16.9±4.2 mmHg (30 minutes) and 15.9±4.6 mmHg (45 minutes). Obtained ICC values were: 0.60 for IOP measurement at 15 minutes, 0.86 for IOP measurement at 30 minutes and 0.84 for IOP measurement at 45 minutes. Considering maximum IOP during the WDT response, ICC value was 0.82. ICC value for IOP fluctuation (maximum - basal IOP) was 0.45. Conclusions: WDT is a reproducible test. IOP measured at 30 minutes after water ingestion and maximum measured IOP after water ingestion were the most reproducible parameters during the WDT. IOP fluctuation showed satisfactory reproducibility.
Keywords: outflow: trabecular meshwork