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A. Ben Said, Y. Lachkar; Selective Laser Trabeculoplasty: Clinical Results - A 4-Year Prospective Study . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2209.
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Purpose: To investigate clinical efficacy and safety of Selective Laser Trabeculoplasty (SLT) to lower intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG). Methods: 60 eyes of 39 patients with uncontrolled POAG by medical therapy. All patients had no past history of conventional or laser ocular surgery. Patients were treated with the Coherent Selecta 7000 (Coherent Inc, Palo Alto, CA) frequency-doubled Q switched Nd: YAG laser. The spot size and the pulse duration are : 400µ and 3ns. A total of approximately 110 non overlapping spots were placed over 360° of the anterior limit of the posterior trabecular meshwork.at energy levels ranging from 0,8 to 1,2 mJ per pulse. The efficacy of the procedure was evaluated after 4 years for 21 eyes. The mean follow up was 33.73 +/- 17.12 months Results: The average patient age was 64.86 ± 12.1 years. The average total energy was 85.9 ± 30.6mJ. Preoperative IOP was 23.44mmHg ± 3.59mmHg. Post-operative IOP at 3 months was 16.29mmHg ± 2.71 mmHg and the average lowering of the IOP was 43.87 %. At 6 months IOP was 16.00 mmHg ± 2.47 mmHg; 15.96 mmHg ± 2.45 mmHg at 1 year; 16.61 mmHg ± 2.74 mmHg at 2 years; 15.46 mmHg ± 2.17 mmHg at 3 years; and 15.94 mmHg ± 2.62 mmHg at 4 years with 46,99 % of average lowering reduction. Conclusions: Selective laser trabeculoplasty appears to be a safe and effective technique to lower the IOP, and could be an alternative to argon laser trabeculoplasty .
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