Abstract
Abstract: :
Purpose: To review clinical outcomes of cataract surgery in patients with sarcoid related uveitis at the New York Eye & Ear Infirmary. Methods: Retrospective chart review of 6 patients (11 eyes) with sarcoidosis-associated uveitis who underwent cataract surgery at the New York Eye & Ear Infirmary over the last 8 years. Outcomes analyzed included patient age, type of uveitis, surgeries performed, initial and final visual acuity, postoperative complications, as well as the use of topical and systemic corticosteroid, nonsteroidal anti-inflammatory, or systemic immunosuppressive agents in the pre-, peri-, and postoperative periods. Results: The ages of the patients ranged from 36 to 72 years (mean: 54.5 yrs.). Mean duration of disease was 10 years. Three patients had bilateral anterior granulomatous uveitis, 2 patients had bilateral pan-uveitis, and 1 patient had bilateral intermediate uveitis. All six patients (11 eyes) underwent cataract extraction with insertion of a posterior chamber lens; other surgical procedures included trabeculectomy with antimetabolite, glaucoma drainage implants, pars plana vitrectomy, and retinal membrane peel. Mean postoperative follow-up was 22 months. The mean initial visual acuity averaged 20/200 (range: 20/60 to hand motion), and mean final visual acuity averaged 20/60 (range: 20/25 to HM). All patients were given systemic corticosteroid and/or immunosuppressive agents to control inflammation during the peri-operative and/or post-operative periods. Poor visual outcomes were related to complications of chronic uveitis, including 4 eyes with cystoid macular edema, 2 eyes with epiretinal membranes, and 8 eyes with uveitic glaucoma. Conclusions: Successful surgical outcomes with minimal postoperative complications were achieved in patients with sarcoid-associated uveitis when inflammation was controlled. Limited visual improvement following surgery was secondary to retina or optic nerve pathology preceding surgery, and related to severity of the uveitis.
Keywords: treatment outcomes of cataract surgery • inflammation • clinical (human) or epidemiologic studies: out