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R. Ursea, R.B. Nussenblatt, J.A. Smith, L. Ayres, R.C. Caruso, H.N. Sen, S.Q. Al-Khatib, S.R. Srivastava, R.R. Buggage; The Role of Ultrasound Biomicroscopy in Assessment of Patients with Anterior Segment Ocular Inflammatory Disease . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2394.
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Purpose:Ocular inflammation affecting the anterior segment can present diagnostic problems because it often involves structures that are not readily accessible by routine examination methods. Our purpose was to assess the utility of ultrasound biomicroscopy (UBM) in the evaluation and management of patients with ocular inflammation involving the anterior segment. Methods:Retrospective, non-comparative review of the medical records of 35 patients with ocular inflammation involving the anterior segment examined with high-resolution ultrasonography using the Humphrey UBM 840 system (Zeiss-Humphrey Instruments, CA) over a period of 5 years. The findings were determined and the clinical relevance of UBM information was analyzed. Results:Abnormalities were found in 25 eyes of 19 patients with the following etiologic diagnoses: anterior uveitis (7), anterior scleritis (11), intermediate uveitis (7). Indications for UBM were: visualization of anterior chamber structures, visualization of ciliary body (CB), pre-operative assessment in eyes with hypotony, or poor visualization of the posterior segment, and for follow-up of documented abnormalities. We found 4 eyes with ciliary body (CB) detachment, 2 cyclodialysis clefts, 1 CB traction band, and 1 CB cyst. The UBM confirmed the clinical diagnosis and was useful only in the follow up of anterior scleritis patients. Unsuspected neoplastic CB masses were identified in 2 patients. In 16 cases UBM failed to reveal any new information. Conclusions:UBM has the ability offer detailed images using high-frequency ultrasound (50 MHz). In our series UBM was able to identify the cause of hypotony, discriminate between the various forms of anterior scleritis and follow and quantify ocular inflammatory changes over time. This noninvasive technique used as a preoperative assessment can provide information critical to surgical planning in eyes hypotony due to ocular inflammatory disease.
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