May 2003
Volume 44, Issue 13
ARVO Annual Meeting Abstract  |   May 2003
Optical Wavefront Analysis of Uncorrected Versus Contact Lens-Corrected Vision
Author Affiliations & Notes
  • J.A. McHale
    Ophthalmology, Ohio State University, Columbus, OH, United States
  • R.G. Lembach
    Ohio State University, Columbus, OH, United States
  • C. Roberts
    Ohio State University, Columbus, OH, United States
  • Footnotes
    Commercial Relationships  J.A. McHale, None; R.G. Lembach, None; C. Roberts, Bausch & Lomb F, C, R.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2539. doi:
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      J.A. McHale, R.G. Lembach, C. Roberts; Optical Wavefront Analysis of Uncorrected Versus Contact Lens-Corrected Vision . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2539.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose: To test the feasibility of Zywave aberrometry to evaluate quality of vision with and without rigid gas-permeable contact lenses (RGPs) in patients with myopic-astigmatism (MA), keratoconus (KC), or penetrating keratoplasty (PK) through the identification and analysis of higher-order aberrations and evaluate the effect of rigid gas-permeable contact lenses (RGPs) on these higher-order aberrations. Methods: Wavefront analysis with the Zywave aberrometer was performed on 14 patients/28 eyes from the Ohio State University Department of Ophthalmology: 5 keratoconus, 6 myopic/astigmatism and 3 penetrating keratoplasty. RGPs were then placed and wavefront analysis was repeated in these eyes. Results: In their native state, 6 of the 10 eyes with keratoconus and 4 of the 6 eyes post-penetrating keratoplasty could be analyzed by Zywave, while all 12 eyes of the patients with myopic-astigmatism were analyzed successfully. With the use of rigid gas-permeable contact lenses, 27 of the 28 subject eyes were successfully analyzed. Mean total wavefront error of KC group was significantly higher than that of MA group (P < 0.0001). The use of RGPs led to a significantly greater decrease in total wavefront error in KC compared to MA (24.32% vs 7.39%, respectively; P = 0.0593). Conclusion: Significant corneal surface irregularity can prevent the extraction and analysis of higher-order aberrations in patients with keratoconus or a corneal graft. Correcting these surface irregularities with a properly fit, rigid gas-permeable contact lens enables successful wavefront analysis to be performed in these populations. Corneal conditions that lead to surface irregularities/irregular astigmatism appear to increase wavefront error. RGPs can not only improve a patient's visual acuity, but can also improve quality of vision by decreasing total wavefront error.

Keywords: cornea: clinical science • keratoconus • contact lens 

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