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R.M. Hazarbassanov, I. Kaiserman, D. Varssano, S. Bishara, A. Wender, D. Bergman, O. Ben- Haim, A. Grinbaum; Comparison of High Order Aberrations Included by Regular LASIK vs. Wavefront Guided LASIK at Various Optic Zones . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2557.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To compare the effect of wavefront guided LASIK vs. standard LASIK on the high order ocular aberrations. Methods: 15 eyes of 8 myopic- astigmatic patients (- 1.12 D to –4.5 D), that underwent wavefront guided LASIK and 16 eyes of 8 myopic- astigmatic patients (-1.5 D to –5.0 D) that underwent standard LASIK (Wavelight-Allegretto scanning- spot laser) were examined using the Wavelight Wavefront analyzer (a Tscherning aberrometer) pre- operatively and 1 month and 3 month post-op. The aberrometry was performed at various optic zones (OZ) ranging from 4 to 6 mm (under cycloplegia). In addition subjective and objective refraction, corneal topography (Oculus) and pupilometry were performed. We looked at the Zernike decomposition of the wave aberration up to the 6 th order and compared the effects of the two types of LASIK on the root mean square (RMS) of the wavefront error for the high order aberrations (3 –6th order) as well as coma and high spherical aberration. Results: While standard LASIK induced a significant increase in high order aberration (from a mean RMS of 0.19 ± 0.02 µm to 0.27±0.03µm). Wavefront guided LASIK did not induce such as increase (a mean RMS change from 0.16±0.02µm to 0.19±0.02 µm). Similarly, an increased in mean coma aberration (from 0.12 to 0.25 µm) was noted in patients treated with standard LASIK, but not with wavefront guided LASIK. A similar trend appeared in the high spherical aberrations. The difference in the RMS of high order aberrations was significantly larger when measured through a 6 mm OZ (0.08µm) compared to a 4 mm OZ (0.04µm). No such effect was noted with wavefront guided LASIK (0.03 µm in both OZ). Conclusions: While correcting defocus and astigmatism, standard LASIK induces a significant increase in high order aberrations and coma especially at optic zones beyond 5 mm, leading to deterioration in the quality of vision especially under mesopic conditions. Those effects can be prevented by wavefront guided LASIK.
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