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C.J. Cheng, J.J. Huang, J. Kanellopoulos; A Prospective Evaluation of Wavefront-guided LASIK with the Allegretto-Wave and the M2 in 150 Eyes . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2603.
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Purpose: To evaluate the safety and efficacy of wavefront-guided LASIK surgery, utilizing the Allegretto-Wave system and the M2 microkeratome. Methods: 150 consecutive LASIK cases for myopic astigmatism underwent wavefront-guided treatment, based on 4 reproducible aberration measurements. We evaluated pre- and post-operative refraction, total high order aberrations (RMSH), flap thickness, diameter, quality, and possible complications. Follow-up was 3-7 months (4.5) Results: 146 eyes were included. The mean values were: refractive error: sphere: –3.80D (-0.50—6.75) and cylinder: -0.85D (0 to –3.75). UCVA improved from 20/200 to 20/18. At 3 months 92% of the eyes were 20/20, 57% 20/15, and 34% 20/10. 100% of eyes were within +/- 0.5D of the refractive goal at 3 months. There was no loss of BCVA in any case. The RMSH decreased from 0.25 to 0.15. There were 4 eyes with increase in RMSH post-op. Conclusions: WaveFront-guided LASIK with the ALLEGRETTO-WAVE system (a 0.9mm flying-spot and 200Hz) and the M2 appears to be safe and very effective for correction of myopic astigmatism. It was demonstrated in this limited clinical study that LASIK with wavefront-guided treatment was able to significantly reduce higher order aberrations in cases of myopic astigmatism.
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