May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
A Prospective, Randomised Comparison of the Amadeus and M2 Microkeratomes in 100 Consecutive LASIK Cases for Myopic Astigmatism
Author Affiliations & Notes
  • D.M. Ledoux
    Ophthalmology, New York University, New York City, NY, United States
  • A. Kanellopoulos
    Ophthalmology, New York University, New York City, NY, United States
  • Footnotes
    Commercial Relationships  D.M. Ledoux, None; A. Kanellopoulos, None.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 2676. doi:
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    • Get Citation

      D.M. Ledoux, A. Kanellopoulos; A Prospective, Randomised Comparison of the Amadeus and M2 Microkeratomes in 100 Consecutive LASIK Cases for Myopic Astigmatism . Invest. Ophthalmol. Vis. Sci. 2003;44(13):2676.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: The prospective, randomised evaluation of the Amadeus (Allergan, CA) and the M2 (Moria, France) microkeratomes in 100 consecutive LASIK procedures. Methods: We evaluated pre- and post-op refraction, wavefront changes (high order aberrations RMSH and coma), flap thickness, diameter and quality as well as complications. Mean follow-up was four months (3-5). Results: 49 eyes were assigned to the Amadeus, and 51 to the M2. Mean values: The mean pre-operative sphere was -4.75D (-1.00 to -12.50) and cylinder -1.25D (-0.25 to -3.75). At 3 months, 87% of the eyes were 20/20, 47% were 20/15, and 32% were 20/10. 100% of eyes were within +/- 1D at three months. Flap Diameter with the Amadeus: 10.8 (+/-0.5)mm, M2: 9.2 (+/-0.5)mm. Flap Thickness with the Amadeus: 155(+/--50) microns, and with the M2: 120(+/-17)microns. Wavefront analysis showed a postoperative increase in coma of only 35% (mean coma of 6% pre-op and 9% post-op). There was a statistical difference in coma-induction and the use of the two microkeratomes in this study (Amadeus 55%, M2 27%). There were three irregular flaps with the Amadeus, 1 with the M2. There were five cases of mild epithelial ingrowth with the Amadeus only. There was a statistical difference in the first post-op day UCVA between the 2 microkeratomes (20/28 with the Amadeus, 20/22 with the M2). No significant complications were noted in this limited group. Conclusions: LASIK utilizing the Wavelight ALLEGRETTO-WAVE laser and any of the two microkeratomes appears to be safe and very effective in correction of myopic astigmatism. Additionally, it appears that the M2 produces a more consistent flap in thickness and may induce less high order aberrations (attributed to the faster surgical pass) and may have a smaller chance for epithelial ingrowth in comparison with the Amadeus (attributed to flap edge contour) in this limited study.

Keywords: refractive surgery: complications • refractive surgery: optical quality • refractive surgery: LASIK 
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