Effect of a Triamcinolone-Assisted Pars Plana Vitrectomy on Proliferative Vitreoretinopathy

Abstract

Abstract: : Purpose: To assess the outcome of a triamcinolone acetonide (TA) assisted-vitrectomy for proliferative vitreoretinopathy (PVR). Method: Thirty-six PVR eyes who received either a TA-assisted pars plana vitrectomy (PPV) or a PPVwithout TA for PVR were studied. Group TA (+) consisted of 15 eyes which received a TA-assisted PPV and group TA (-) consisting of 21 eyes which received a PPV with no TA. The follow-up ranged from 6 to 24 months (mean follow-up 12.2 months). The following postoperative findings were examined; the best and last corrected visual acuity, re-operation ratio, intraocular pressure (IOP) elevation, corneal pathology (persistent corneal erosion or ulcer, corneal opacity), and infection. This study is retrospective, noncomparative, interventional consecutive case series. Results: Retinal reattachment by a single operation was obtained in 67% of the group TA (+) eyes and 24% of the group TA (-) eyes (P=0.19). Final retinal attachment ratio was 93% and 57% respectively. Seventy-three percent of the eyes in group TA (+) and 52% of the eyes in group TA (-) had the improved vision after surgery. The group TA (+) showed the significantly low re-operation rate in comparison to the group TA (-) (p=0.018). After the operation, one eye of group TA (+) and one eye of group TA (-) had an IOP elevation, however, they were both well controlled by eyedrops. No other complications were found in each group. Conclusion: TA-assisted vitrectomy had more therapeutic benefits than a PPV without TA for PVR especially in a re-operation ratio. The toxicity of TA was not apparent during the observation period.

Keywords: proliferative vitreoretinopathy • clinical (human) or epidemiologic studies: tre • vitreoretinal surgery