Visual Outcome after Pars Plana Vitrectomy with Membrane Peeling in Patients with Diabetic Versus Nondiabetic Related Cystoid Macular Edema

Abstract

Abstract: : Purpose: To determine the visual outcomes after pars plana vitrectomy (PPV) and membrane peeling (Mx) in patients with diabetic versus nondiabetic related cystoid macular edema (CME). Methods: The charts of 24 patients with 26 CME eyes underwent PPV and Mx between 1997 to 2002 were reviewed. The logMAR equivalent was used to calculate average mean visions. The patients were self-paired to compare the mean vision pre and post operatively. The paired T-test was used to assess the statistical significance of the difference between the mean visions before and after surgery. Student T test was used to assess the statistical significance of the difference between the increased visions in the eyes with or without diabetic related CME. Results: Mean visions (mean± SD) The post-op logMAR equivalent vision was significantly increased (P=0.019) for all 26 CME eyes and was more significantly increased (P=0.004) in eyes with nondiabetic related CME. However, the post-op logMAR equivalent vision in eyes with diabetic related CME was not significantly increased (P=0.80). The logMAR equivalent vision increase between the diabetic and nondiabetic related CME eyes was significant different (P=0.026). Conclusions: In 26 patients with CME who underwent PPV and Mx, the visual outcome appears significantly different in patients based on the absence or presence diabetic related CME. The post-op vision was significant increased in patient with nondiabetic related macular edema while no significant change in vision was demonstrated in patients with diabetic related CME.  

Keywords: vitreoretinal surgery • retina • diabetes