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S. Roy, E. Adjadj, A. Mermoud; Images of New Drainage Device in Non-penetrating Glaucoma Surgery . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3301.
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Purpose: To present the technical features of a new type of glaucoma space maintainer in non-penetrating glaucoma surgery. Methods: Technical features and preliminary results on an animal model of a PMMA drainage device are presented. The implant has the shape of an X (4 by 4 mm, 500 µm thick). The material has been studied by scanning electron microscopy for surface analysis and inflammatory response. In experimental glaucoma surgery, thirty implants have been inserted in thirty rabbit eyes as a space maintainer in the sclera space. Ten were coated with hyaluronic acid, twenty had no surface treatment. After surgery, scanning electron microscopy of implants removed at 1-2-3 months after surgery have been performed. Alterations of the surface and inflammatory reactions with fibroblasts growth have been documented Results: Before surgery, the surface of the implant was smooth. At 1 to 3 months after surgery, the surface has been invaded by few fibroblast-like cells, and images of thin biofilm could be occasionally detected. Nevertheless the material used showed good biocompatibility, similar to these of IOL Conclusions: The X PMMA drainage device is a new type of space maintainer that might safely be used in non-penetrating glaucoma surgery. It is easy to produce and the costs can be kept low, allowing a wide use in developping countries.
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