Optical Coherence Tomography (OCT-3) Can Detect a Retinal Macular Thickness Difference Between Ocular Hypertensive and Normal Eyes

Abstract

Abstract: : Purpose: To compare macular thickness between ocular hypertensive (OHT) and normal eyes. Methods: OHT patients and normal subjects were enrolled. Complete ophthalmic examinations, achromatic automated perimetry and OCT-3 imaging using the fast macular scan were performed in all patients. Macular thickness measurements were compared between groups using t-test. Results: Thirty-six eyes of 36 patients (16 normal, 20 OHT) were enrolled. OHT patients were older than normal subjects (56.5 ± 14.7 vs. 39.4 ± 16.6, p=0.002, t-test). The mean superior and mean temporal outer macular thicknesses in the 3.5 mm map circle diameter in the OHT group (270.2 ± 20.3 and 254.9 ± 19.9 µm, respectively) were significantly thinner than in the normal group (283 ± 13.5 and 268.4 ± 14.8 µm, respectively) (p=0.04 and p=0.03, t-Test, respectively). The mean superior outer macular thickness in the 6 mm map circle diameter in the OHT group was thinner than in the normal group (233.7 ± 17.5 vs. 246.3 ± 12.8 µm, p=0.03, t-Test, respectively). Conclusions: There is a macular thickness difference between OHT and normal eyes.

Keywords: imaging/image analysis: clinical • imaging methods (CT, FA, ICG, MRI, OCT, RTA, S • clinical (human) or epidemiologic studies: sys