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J.G. Renard, F. May, P. Clerc, J.C. Rigal-Sastourne, S. Monroux-Rousseau, C. Leduc, K. Reda, J.F. Maurin; Reproducibility of Measurements With the Scanning Laser Polarimetry With Variable Corneal Compensation (GDx-VCC) . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3373.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose:To evaluate the reproducibility of measurements by the scanning laser polarimeter with variable corneal compensation(GDx-VCC)in healthy subjects and patients with glaucoma.The authors also assessed the variance of measurements between separate operators Methods:Three independent retardation maps of the peripapillary retina of 62 normal eyes and of 64 eyes with OHT(32) or moderate glaucoma(32),were acquired by two experienced operators.For each operator and in each group reproducibility of measurement ellipse and of other available parameters was expressed in term of coefficient of variance.Using multivariate analysis of variance, the authors determined the variance of measurements between the two operators. Results:The reproducibility of measurements ellipse varied for each operator.Mean coefficients of variance were 4,35%(4,3-4,4%) for operator 1 and 3,9%(3,7-4,1%) for operator 2 in the healthy volunteers, and 3% for operator 1 and 3,1%(2,8-3,5%) for operator 2 in the patients with OHT or glaucoma.For each operator and in the two groups of subjects the reproducibility of the other available parameters was good without statistically significant difference(intra-observer)between the three measurements.Between the two operators there was a small,but statistically significant inter-observer difference of 40 microns(p<0.001).Parameters assessed were statistically not influenced by this inter-observer variability of the measurement ellipse. Conclusions:These results suggest that the GDx-VCC provides reproductible measurements.The reproducibility was similar between healthy subjects and patients with OHT or glaucoma.Measurements obtained by separate operators are similar.
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