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E.Z. Blumenthal, S. Frenkel; Inter-Device Reproducibility of the Scanning Laser Polarimeter with Variable Cornea Compensation . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3390.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate the inter-device reproducibility of retinal nerve fiber layer (RNFL) thickness measurements obtained with the commercially available GDx-VCC, a scanning laser polarimeter with variable (individualized) corneal compensation. Methods: One eye each, from three normal subjects was tested on 13 different GDx-VCC devices, on the same day, by an experienced operator. Reproducibility for each of 5 GDx parameters was calculated. Results: For each of five tested GDx parameters, the averaged standard deviation (µm), coefficient of variation and 95% confidence interval range (µm), respectively, were: TSNIT average: 3.18µm, 5.06%, 3.84µm; superior average: 3.99µm, 5.27%, 4.82µm; inferior average: 4.55µm, 6.08%, 5.50µm; TSNIT standard deviation: 1.89µm, 8.63%, 2.92µm; the Number (also referred to as nerve fiber indicator): 4.71, N/A, 5.69. For each of the 5 GDx parameters, repeated measures ANOVA was non-significant for inter-device differences. Conclusions: With the commercially available GDx-VCC our results indicate that the RNFL measurements appear reproducible across devices.
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