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C.D. Scholda, M. Wirtitsch, B. Hermann, A. Unterhuber, H. Sattmann, M. Stur, T. Ko, O. Findl, J.G. Fujimoto, W. Drexler; Macular Hole Imaging Using Ultrahigh Resolution Optical Coherence Tomography . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3636.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To demonstrate the clinical feasibility of ultrahigh resolution ophthalmic optical coherence tomography (OCT) for investigating retinal morphology of different stages of macular holes. Methods: A compact, new generation ultrahigh resolution ophthalmic optical coherence tomography (OCT) system has been used for imaging different stages of macular holes. 60 eyes with macular holes of different stages of 38 patients were examined. The informations obtained were evaluated in regard to changes in retinal structure correlated with the formation of a macular hole. Results: Ultrahigh resolution ophthalmic OCT enables the in vivo visualization of intraretinal structures and retinal morphology in macular holes. Especially the alteration and disintegration of deeper retinal layers as well as the formation of intraretinal spaces can be correlated to retinal structures. There seems to be also an alteration of the external limiting membrane (ELM) and inner / outer segments (IS/OS) of the photoreceptor layer correlated with the development of macular holes. Conclusions: Ultrahigh resolution ophthalmic OCT has the potential to visualize intraretinal morphology in patients with macular holes in an unprecedented way. This could have implications on better understanding of this disease, for an improved staging system as well as on surgical therapy by providing additional information with better prediction of the prognosis.
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