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K. Hosseini, A.I. Kholodnykh, I.Y. Petrova, R.O. Esenaliev, F. Hendrikse, M. Motamedi; Optical Coherent Tomography for in vivo High Resolution Quantitative Imaging of the Corneal Function . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3667.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate the feasibility of optical coherent tomography (OCT) in studying the corneal physiology. Methods: Rabbit cornea dehydration was induced in vivo using either Ophthalgan or simple surface evaporation at room temperature. OCT signals were used to monitor the change in thickness and the optical scattering of the cornea during de- and rehydration processes of the cornea. Results: An accurate measurement of the cornea thickness and scattering was realized while an overshoot was detected during the rehydration process of the cornea. A direct relationship was found between the amount of light backscattering of the cornea and its actual level of hydration. Conclusions: OCT has the potential to be a noninvasive tool for accurate high resolution measurement of corneal hydration.
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