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G.S. Rengifo, R. Suarez, M.O. Niño, E.L. Graue; Clinical Ophthalmologic and Genetic Study of the Corneal Dystrophies in Mexican Population . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3870.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: to know clinical ophthalmologic and genetic behavior of the corneal dystrophies in Mexican population, from the Institute of Ophthalmology. Method:We review the records of the patients with corneal dystrophy between 1992 to 2002.Patients with confirm diagnosis of corneal dystrophy were submitted to protocol. The B.C.V.A., intraocular pressure, anterior segment biomicroscopi, specular microscopy and pachimetry were evaluated. All first degree relatives were submitted to ophthalmologic complete examination. The genetic records were performed for all subjetcs. Results:We select 15 index cases and 120 relatives. Dystrophies:Fuchs 7(46.6%),E.C.H.D.3(20%), Lattice 2(13.13%), P.P.D 2(13.3%),Avellino 1(6.6%). Average age of the index case 57.3 years(range 6-79),relatives average age 31.3 years(range 2-70),females 6(40%), males 9(60%). 7 affected members in two families with lattice. Every one had varying degrees of bilateral corneal clouding. Pachimetry mean 545. Specular microscopy: from no visible to minimal changes. Conclusions:We found only 13.3% family cases, we believe that its because the age of the relatives no exceed the age of initial manifestations of different corneal dystrophies. The most frecuent dystrophy was Fuchs.
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