May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Phototherapeutic Keratectomy (o-PTK) for Recurrent Granular and Lattice Dystrophy After Corneal Transplantation Using the 193 nm Excimer Laser- Long-Term Results of 20 Consecutive Procedures
A.U. Hafner; B. Seitz; A. Langenbucher; G.O. Naumann
Author Affiliations & Notes
  • A.U. Hafner
    Ophthalmology, University of Erlangen, Erlangen, Germany
  • B. Seitz
    Ophthalmology, University of Erlangen, Erlangen, Germany
  • A. Langenbucher
    Ophthalmology, University of Erlangen, Erlangen, Germany
  • G.O. Naumann
    Ophthalmology, University of Erlangen, Erlangen, Germany
  • Footnotes
    Commercial Relationships  A.U. Hafner, None; B. Seitz, None; A. Langenbucher, None; G.O.H. Naumann, None.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 3871. doi:
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      A.U. Hafner, B. Seitz, A. Langenbucher, G.O. Naumann; Phototherapeutic Keratectomy (o-PTK) for Recurrent Granular and Lattice Dystrophy After Corneal Transplantation Using the 193 nm Excimer Laser- Long-Term Results of 20 Consecutive Procedures . Invest. Ophthalmol. Vis. Sci. 2003;44(13):3871.

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Abstract

Abstract: : Purpose: Phototherapeutic keratectomy (PTK) may be applied to treat recurrent epithelial defects (e-PTK) or superficial corneal opacities (o-PTK). The purpose of this prospective study was to investigate morphological and functional long-term results after o-PTK in recurrent granular and lattice dystrophy on corneal grafts. Patients and Methods: Between 02/1989 and 11/2002, 20 out of 317 PTKs were performed because of recurrent granular or lattice dystrophy after corneal transplantation. Patients were divided into two groups: group 1 included 14 PTKs performed because of recurrent granular dystrophy on the corneal graft, group 2 6 PTKs because of recurrent lattice dystrophy on the corneal graft. The intended laser ablation after epithelial debridement and pannectomy varied from 10-80 µm (group 1) and from 20-80 µm (group 2). We used the slit-scanning-mode of the Zeiss-Meditec laser with a repetition rate of 20/s or 25/s, a mean pulse energy of 15.7 mJ (group 1), 22.2 mJ (group 2) and a mean pulse rate of 2027 (231-6370) (group 1), 1964 (815-3806) (group 2). Results: Mean follow-up was 3.0+/-2.4 (max. 6.7) years (group 1) and 2.9+/-2.8 (max. 6.9) years (group 2). Best-corrected visual acuity improved from 0.3+/-0.2 to 0.5+/-0.1 (group 1) and from 0.25+/-0.2 to 0.4+/-0.2 (group 2). Median spherical equivalent did not change significantly in group 1 (–0.89 diopters (D) preoperatively, –0.95 D postoperatively) and decreased from 0.5 D to 0.0 D in group 2. Mean central keratometric power decreased from 44.2+/-4.8 D to 42.5+/-4.9 D (group 1) and did not change significantly in group 2 (41.3+/-1.2 D pre-, 41.6+/-2.6 D postoperatively). In group 1 we noticed 4 recurrences (28%) after a mean period of 2.4 (2.0–3.3) years, but no recurrence in group 2. Conclusion: In superficial opacities, caused by recurrent granular or lattice dystrophy after corneal transplantation, o-PTK using the 193 nm excimer laser usually results in a moderate improvement of best-corrected visual acuity without significant changes of spherical equivalent and central corneal power. Thus, a repeat penetrating keratoplasty can be avoided or at least delayed in most cases.

Keywords: clinical (human) or epidemiologic studies: tre • laser • cornea: stroma and keratocytes 
© 2003, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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