Evaluation of Renal Function and Visual Outcome in Vitrectomy Cases with Diabetic Macular Edema

Abstract

Abstract: : Purpose: To evaluate the relationship between general condition and postoperative ophthalmological outcome in cases underwent vitrectomy for diabetic macular edema (DME). Materials and Methods: Among 73 vitrectomized eyes of 47 cases with DME, analysis was made in 34 eyes of 21 cases followed up more than six months in which diabetes has been strictly treated and each renal function has been exactly evaluated. Examined factors consisted of FBS, HbA1c, duration of DM, nephropathy and pre and postoperative visual acuity, retinal thickness (by OCT), fluorescein angiographic findings and accumulation of hard exudates in the macular area. Results: Statistical analysis revealed that favorable surgical effects such as increased visual acuity (2 lines or more), discreased retinal thickness were obtained in cases with their renal function was stageII (no proteinuria) or earlier. And also hard exudates deposition did not increase or disappeared in such cases. On the otherhand, in case with severe renal failure (stageIIIa or more) visual acuity decreased accompanying with increased hard exudates deposition in the fovea. These findings were statistically significant. Conclusion: It seems to be logical to assume that vitrectomy for DME may be of benefit to the patients without proteinuria.

Keywords: diabetes