Abstract
Abstract: :
Purpose: Optical Coherence Tomography (OCT) is in widespread qualitative and quantative use in the assessment of diabetic macular oedema (DMO). There are however very few data regarding the different OCT patterns which may be observed in this context. The systematic evaluation of new treatments for DMO dictates that a better understanding is developed. Methods: 100 subjects with DMO underwent OCT scanning using six 5.92mm radial line scans, at 300 intervals, centred on the fovea. The following features were assessed: the pattern and extent of intraretinal fluid, foveal contour, vitreomacular interface pattern (VMIP) and the presence or absence of subfoveal fluid. The concordance of these features between the 6 scans was determined. Results: n=100 (M:F=60:40; mean age 66± 10 years; Type I: Type II DM= 3:97; Etnicity: Caucasian=93, Asian =4, Afrocribbean = 3; Oriental = 0) OCT Patterns: Table 1 Concordance between all 6 scans was as follows: Extent of intraretinal oedema =97%; Intraretinal oedema pattern=76%; Foveal contour= 66%. Subfoveal fluid and the VMIP were only detected in 12% and 33% of subjects respectively with poor concordance between the 6 scans (2% and 3%) Conclusions: DMO demonstrates heterogenous OCT features. A single scan may be adequate to describe the pattern and extent of DMO but multiple radial scans are needed to assess the foveal contour, VMIP and foveal detachment.
Keywords: diabetic retinopathy • imaging/image analysis: clinical • imaging methods (CT, FA, ICG, MRI, OCT, RTA, S