Purchase this article with an account.
S. Machida, T. Fujiwara, T. Gotoh, Y. Hasegawa, A. Gotoh, Y. Tazawa; Prolonged Hyperfluorescence After Vitreoretinal Surgery Assisted by Indocyanine Green (ICG) . Invest. Ophthalmol. Vis. Sci. 2003;44(13):4035.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Purpose: To investigate how long ICG dye used in vitreoretinal surgery remains in the ocular fundus and how the remained dye interferes with post-operative ICG fundus angiographic findings. Methods: Subjects were 12 eyes consisting of eight eyes with macular hole, three with epiretinal membrane and one with an intraocular foreign body. The patients underwent vitrectomy facilitated by an intraocular administration of ICG. Pre- and postoperative fundus pictures were taken from those eyes by an infrared sensitive video camera. In two out of the cases, ICG angiography was carried out at two weeks and three months after the surgery. Results: At one month after the surgery, diffuse retinal hyperfluorescence was observed throughout the posterior pole of the ocular fundus including the optic disc in the all cases. The area where macular hole existed prior to the surgeries revealed hyperfluorescence in six out of eight (75%) eyes with macular hole. The diffuse and macular hyperfluoresce became less prominent with time postoperatively while the optic disc hyperfluorescence persisted for 12 months in the all cases. In the early phase of ICG angiography of the two eyes at two weeks postoperatively, the retinal and choroidal circulation could be observed, but in the middle phase, the choroidal veins were hardly visible. The angiographic pictures of the late phase mimicked those seen before intravascular administration of ICG. Even at three months following the surgery, the optic nerve head revealed hyperfluorescence in the middle and late phases of the ICG angiography. Conclusions: The residual ICG in the ocular fundus produced prolonged hyperfluorescence after the surgery. This abnormal condition affected ICG angiographic findings in the middle and late phases.
This PDF is available to Subscribers Only