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R. Chandrashekhar, F.M. Rauscher, S. Fekrat; Long-term Outcomes Following Laser Chorioretinal Anastomosis for Perfused Central Retinal Vein Occlusion . Invest. Ophthalmol. Vis. Sci. 2003;44(13):4058.
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Purpose: To provide long-term outcomes after laser-induced chorioretinal venous anastomosis (CRA) in consecutive eyes with perfused central retinal vein occlusion (CVO) and poor visual acuity (VA ≤ 20/400). Methods: Retrospective review of eyes with CVO and pre-treatment VA ≤ 20/400 treated with one or more laser-induced CRA and followed for at least 12 months was conducted. All eyes were treated with argon green, 6 W, 50 u, 0.2 sec in a standard fashion. Results: 12 eyes were identified, with a mean pretreatment VA of 20/590 (range, 20/400 to 20/8000) (logMAR 1.47±0.12). All 12 eyes had cystoid macular edema (CME). Mean follow-up was 24 ± 5 months. Three eyes (25%) had VA improvement of at least 2 lines, and the remaining nine eyes had stable (unchanged) VA. Mean final VA was 20/340 (range 20/250 to 20/600) (logMAR 1.23±0.04, p<0.01 vs. intial VA), with the greatest improvement in patients with the worst pretreatment VA (Table). Disappearance of CME was noted in 7/12 patients (58%), with CME changes documented by optical coherence tomography in 6 cases. Anterior and posterior neovascularization occurred in one eye, after 4 years. All 12 eyes remained non-ischemic during the follow-up period. Conclusions: Laser-induced chorioretinal anastomosis in eyes with perfused CVO and low VA may improve long-term vision in 25% of cases, is associated with resolution of CME, and may prevent ischemic progression. View OriginalDownload SlideView OriginalDownload Slide
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