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M.M. Joshi, M. Subramanian, P. Salvetti, E. Reichel; Subthreshold Infrared Footprinting Technique (SIFT) With Indocyanine Green . Invest. Ophthalmol. Vis. Sci. 2003;44(13):4064.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To describe a novel technique for localizing subthreshold, infrared (810 nm) laser treatment. Methods: A series of illustrative cases employing subthreshold, infrared (810 nm) laser treatment was performed. Treatment methods included transpupillary thermotherapy for occult choroidal neovascularization, focal subthreshold laser treatment for classic choroidal neovascularization, and focal/grid treatment of diabetic macular edema. Images were then obtained with digital angiography or the scanning laser ophthalmoscope (SLO). Results: Hypofluorescent areas corresponding to laser treatment areas were identified in post-operative indocyanine green (ICG) angiograms despite lack of any changes on fundoscopy. Reinjection of ICG showed isofluorescence of the choriocapillaris that was consistent with the pre-operative appearance, suggesting that the choriocapillaris remained intact. Conclusions: This case series shows that SIFT is a useful means for localizing subthreshold infrared laser photocoagulation. This technique may become highly useful if subthreshold infrared laser for choroidal neovascularization, diabetic macular edema, and drusen become accepted as treatment standards.
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