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C. Erb, M. Meyer, A.U. Bayer, A. Schroeder; Are There Any Differences in Color Vision between Patients with Coronary Artery Disease (CAD) and Patients with Primary Open Angle Glaucoma and CAD? . Invest. Ophthalmol. Vis. Sci. 2003;44(13):4352.
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Purpose: To differentiate color vision defects in primary open-angle glaucoma (POAG) from that of coronary artery disease. Methods: The morphological status, visual acuity, intraocular pressure, and the cup/disc-ratio of the optic nerve were examined in all groups. In addition, white-on-white perimetry was applied in the glaucoma patients. Color vision, examined by the hue arrangement test Roth 28-hue (E) desaturated was measured monoculary under standard conditions in both eyes. The background was a black cardboard; illumination was provided by fluorescent light sources with a balanced spectral distribution and a color-rendering index of 93 (Osram L36W/12 LDL Daylight; 5500 K, 2000 lux). Results: Twenty patients (m:f=10:10; mean age=68+/-8 years) with POAG and a CAD (group 1), 28 patients with CAD without glaucoma (28 men; mean age=66+/-5 years; group 2) and 38 healthy controls (m:f=23:15; mean age=66+/-5 years; group 3) were examined. Visual acuity was similar in all three groups. However, the POAG-patients had a higher intraocular pressure, a larger cup/disc-ratio and scotomas in the visual field. Testing of color vision revealed a significantly higher error score in group 1 and 2 than the control group (median+/-mean absolute deviation=114+/-53; p<0.001). No differences were found between group 1 (240+/-59) and group 2 (186+/-102) (p=0.2). Conclusions: Coronary artery disease causes high error scores in color vision testing. In combination with POAG, no additional disturbance in color vision could be found. This has to be taken into account in color vision testing in glaucoma patients.
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