May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Same-Size Donor Corneas for Myopic Keratoconus
Author Affiliations & Notes
  • S. Shimmura
    Department of Ophthalmology, Tokyo Dental College, Ichikawa, Japan
  • M. Ando
    Department of Ophthalmology, Tokyo Dental College, Ichikawa, Japan
  • M. Ishioka
    Department of Ophthalmology, Tokyo Dental College, Ichikawa, Japan
  • J. Shimazaki
    Department of Ophthalmology, Tokyo Dental College, Ichikawa, Japan
  • K. Tsubota
    Department of Ophthalmology, Tokyo Dental College, Ichikawa, Japan
  • Footnotes
    Commercial Relationships  S. Shimmura, None; M. Ando, None; M. Ishioka, None; J. Shimazaki, None; K. Tsubota, None.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 4675. doi:
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    • Get Citation

      S. Shimmura, M. Ando, M. Ishioka, J. Shimazaki, K. Tsubota; Same-Size Donor Corneas for Myopic Keratoconus . Invest. Ophthalmol. Vis. Sci. 2003;44(13):4675.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To determine the efficacy of using same-size donor grafts for keratoconus patients with axial myopia. Methods: One hundred and forty two eyes of 136 consecutive keratoconus patients were enrolled in a prospective interventional case series study. Penetrating keratoplasty (PKP) was performed by 3 skilled surgeons using the same technique with a single running 10-0 nylon suture. Donor button size was determined by a study protocol, where a same-size donor was used for eyes with an axial length (AXL) longer than 24.50 mm, while a 0.25 mm over-sized donor was used for eyes shorter than 24.49 mm. Results: Of the 142 consecutive eyes, 123 eyes were operated according to protocol. The average post-operative SE was -3.9 ± 3.2 D, with an average uncorrected visual acuity of 0.43 (0.95 average corrected). Post-operative SE correlated inversely (r=0.46) with pre-operative axial length (AXL) expressed by the equation: SE= -0.15 (AXL)² + 6.40 (AXL) - 71.82. Graft rejection was observed in 7 eyes (5.7%) and glaucoma in 2 eyes that required surgery. Conclusions: Using same-size donor grafts in keratoconus patients with a long visual axis is a safe and effective procedure in reducing post-operative myopia.

Keywords: keratoconus • cornea: clinical science • refractive error development 
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