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M.B. Strominger, K.B. Miller; Treatment of Strabismus and Anisometropic Amblyopia in Microphthalmia With Cyst . Invest. Ophthalmol. Vis. Sci. 2003;44(13):4814.
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Purpose:Microphthalmia with cyst is a rare condition whereby a posterior cystic structure develops secondary to the proliferation of neuroectoderm through a closure defect in the embryonic optic fissure. Visual potential is limited secondary to optic nerve dysfunction plus maldevelopment of other structures including the cornea, anterior segment and retina. Methods:We report the amblyopic treatment and surgical correction of a 3-year-old with unilateral microphthalmos with cyst and esotropia. Results:At birth the patient had non-recordable visual evoked potentials (VEP) in the affected eye. With correction of hyperopic anisometropia, patching, and surgical correction of a 50 prism diopter esotropia, the visual acuity developed to 20/160 at 5 inches and ocular alignment to within 10 prism diopters of midline Conclusions:Visual acuity and strabismic alignment can be improved in children with appropriate amblyopic treatment and surgical alignment.
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