May 2003
Volume 44, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2003
Photodynamic Therapy for Choroidal Neovascularization in Multifocal Choroiditis
M.B. Parodi; L. Di Crecchio; P. Lanzetta; A. Polito; F. Bandello; G. Ravalico
Author Affiliations & Notes
  • M.B. Parodi
    Eye Clinic, University of Trieste, Trieste, Italy
  • L. Di Crecchio
    Eye Clinic, University of Trieste, Trieste, Italy
  • P. Lanzetta
    Eye Clinic, University of Udine, Udine, Italy
  • A. Polito
    Eye Clinic, University of Udine, Udine, Italy
  • F. Bandello
    Eye Clinic, University of Udine, Udine, Italy
  • G. Ravalico
    Eye Clinic, University of Udine, Udine, Italy
  • Footnotes
    Commercial Relationships  M.B. Parodi, None; L. Di Crecchio, None; P. Lanzetta, None; A. Polito, None; F. Bandello, None; G. Ravalico, None.
Investigative Ophthalmology & Visual Science May 2003, Vol.44, 4895. doi:
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      M.B. Parodi, L. Di Crecchio, P. Lanzetta, A. Polito, F. Bandello, G. Ravalico; Photodynamic Therapy for Choroidal Neovascularization in Multifocal Choroiditis . Invest. Ophthalmol. Vis. Sci. 2003;44(13):4895.

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Abstract

Abstract: : Purpose: Choroidal neovascularization (CNV) is the most frequent cause of visual acuity loss in Multifocal Choroiditis (MC). Aim of the study is to report the effects of photodynamic therapy (PDT) with verteporfin on subfoveal CNV secondary to MC. Methods: A prospective study of 12 eyes of 12 patients with subfoveal CNV in CM was planned. Clinical and angiographic examinations were carried out before PDT and 3, 6, 9 and 12 months after PDT. PDT was performed according to TAP protocol. Best corrected visual acuity was measured using ETDRS chart. Results: The mean age of the patients was 44.9, with 10 females and 2 males. A mean of 1.75 (range:1-3) treatments were performed by the 12-month visit. Baseline and final best corrected visual acuity were respectively 0.55 LogMAR and 0.58 LogMAR. At the 12-month control best corrected visual acuity improved by at least 1,5 lines in 1 patient (8.3%), stabilized in 9 patients (75%) and decreased in 2 cases (16.6%). There were no treatment-related side effect. Conclusions: Even though the number of the patients is limited and there is no control group, our preliminary report indicates that PDT is useful in stabilizing visual acuity in eyes affected by subfoveal CNV in MC.

Keywords: choroid: neovascularization • photodynamic therapy 
© 2003, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2024 Association for Research in Vision and Ophthalmology.
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