December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
Mapping Retinal Nerve Fiber Layer Thickness and Internal Reflectivity to the Visual Field
Author Affiliations & Notes
  • H Ishikawa
    New York Eye & Ear Infirmary New York NY and New York Medical College Valhalla NY
  • S Piette
    New York Eye & Ear Infirmary New York NY and New York Medical College Valhalla NY
  • JM Liebmann
    New York Eye & Ear Infirmary New York NY and New York Medical College Valhalla NY
  • R Ritch
    New York Eye & Ear Infirmary New York NY and New York Medical College Valhalla NY
  • Footnotes
    Commercial Relationships    H. Ishikawa, pending P; S. Piette, None; J.M. Liebmann, pending P; R. Ritch, pending P. Grant Identification: Support: NY Glaucoma Research Institute and NY Eye and Ear Infirmary, NY, NY.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 251. doi:
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    • Get Citation

      H Ishikawa, S Piette, JM Liebmann, R Ritch; Mapping Retinal Nerve Fiber Layer Thickness and Internal Reflectivity to the Visual Field . Invest. Ophthalmol. Vis. Sci. 2002;43(13):251.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To assess sector peripapillary OCT information usinga visual field mapping system on correlation of retinal nervefiber layer (RNFL) measurements and visual function.Methods:OCT (Zeiss-Humphrey Systems Inc., Dublin, CA) was used to assessthe peripapillary RNFL in normal and glaucomatous eyes. Circularscan data were divided into 6 sectors based on an achromaticautomated perimeter mapping concept introduced by Garway-Heathet al (Ophthalmology 2000;107:1809-15; see figure).Results:We enrolled 106 eyes of 106 patients (41 normal, 65 glaucoma;mean age 56.1 ± 11.9 (SD) years (range 24 to 78 yrs.)).Mean RNFL index of each sector showed significant correlationwith sensitivity of the corresponding visual field area (p<0.0001,Spearman's rank correlation; see table). Combined mean RNFLthickness of areas 2 and 4 showed the best correlation withMD and CPSD among all combinations of quadrants or clock hoursectors (rs=0.76 (MD), -0.73(CPSD)).Conclusion: The proposedsector analysis may be more suitable for glaucoma assessmentthan the conventional OCT RNFL analysis. These data suggestthat use of arc scan rather than circular scan data is desirablefor evaluating glaucomatous RNFL. Table  

 

Keywords: 430 imaging/image analysis: clinical • 484 nerve fiber layer • 624 visual fields 
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