December 2002
Volume 43, Issue 13
ARVO Annual Meeting Abstract  |   December 2002
Medication Adherence Barriers In Patients With Glaucoma
Author Affiliations & Notes
  • JC Tsai
    Ophthalmology Harkness Eye Inst/Columbia Univ New York NY
  • SE Ramos
    Vanderbiilt University Medical Center Nashville TN
  • CA McClure
    Vanderbiilt University Medical Center Nashville TN
  • JW Pichert
    Vanderbiilt University Medical Center Nashville TN
  • DG Schlundt
    Vanderbiilt University Medical Center Nashville TN
  • Footnotes
    Commercial Relationships   J.C. Tsai, None; S.E. Ramos, None; C.A. McClure, None; J.W. Pichert, None; D.G. Schlundt, None. Grant Identification: Support: Homer McK. Rees Scholar Award
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 277. doi:
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    • Get Citation

      JC Tsai, SE Ramos, CA McClure, JW Pichert, DG Schlundt; Medication Adherence Barriers In Patients With Glaucoma . Invest. Ophthalmol. Vis. Sci. 2002;43(13):277.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose: To systematically identify and describe the obstacles to medication adherence (compliance) for patients with glaucoma (i.e. develop a taxonomy of barriers). Methods: Structured interviews were conducted with 49 patients with a diagnosis of glaucoma. Subjects' responses were recorded verbatim on an interview form as well as recorded on audiotapes for later reference. Situational obstacles to medication adherence were elicited. Using hierarchical cluster analysis, the situational descriptions were stratified, grouped, and analyzed by frequency distribution. Results: Seventy-two (72) unique obstacles to adherence were reported. These were then grouped into four (4) distinct and separate categories. Situational and environmental factors accounted for the greatest number of obstacles (41 of 72; 57%) and involved major life events (e.g. illness, hospitalization, etc.), travel/away from home, competing activities, and change in the daily routine. Difficulties associated with the medication regimen (e.g. cost, complexity, and side-effects of the drugs) accounted for 18 of 72 situational barriers (25%). Individual patient factors (10 of 72; 14%), and provider factors (2 of 72; 3%) were less commonly cited. Conclusion: Significant barriers to regimen adherence for patients with glaucoma exist in addition to those cited by previous ophthalmic studies. A systematic classification (i.e. taxonomy) of these barriers was formulated to assist in optimizing patient education and problem solving regarding prescribed therapeutic regimens.

Keywords: 351 clinical (human) or epidemiologic studies: health care delivery/economics/manpower 

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