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Y Siddiqui, DO Hodge, JD Cameron, DH Johnson; What Is the Risk of Developing Pigmentary gGaucoma from Pigment Dispersion Syndrome? . Invest. Ophthalmol. Vis. Sci. 2002;43(13):285.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To determine the probability of converting to pigmentary glaucoma (PG) from pigment dispersion syndrome (PDS). Methods: Retrospective population-based study of all newly diagnosed cases of PDS and PG from 1976-1999 in Olmsted County, MN. Criteria for PDS were 2 of 3 signs: iris TI defects, Krukenberg spindles, heavy TM pigment. Criteria for PG were: PDS and 2 of 3 findings: IOP≷21 mmHg, disc damage, visual field loss. Kaplan-Meier survival curves were used to determine the probability of conversion to PG. Results: 119 patients were newly diagnosed with PDS over the 23 year period. Of these, 31 developed PG or PDS with elevated IOP requiring therapy. The probability of converting to PG was 13% at 5 years and 23% at 15 years. An additional 26 patients were found to have pigmentary glaucoma without a previous diagnosis of PDS during this period. Mean age at diagnosis of PDS was 41 years, PG was 44 years. 57% of PDS patients were male, 87% of PG patients were male. Conclusion: The risk of developing PG from PDS is 13% at 5 years and 23% at 15 years.
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