December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
What Is the Risk of Developing Pigmentary gGaucoma from Pigment Dispersion Syndrome?
Author Affiliations & Notes
  • Y Siddiqui
    Ophthalmology
    Mayo Clinic Rochester MN
  • DO Hodge
    Biostatistics
    Mayo Clinic Rochester MN
  • JD Cameron
    Ophthalmology
    Mayo Clinic Rochester MN
  • DH Johnson
    Ophthalmology
    Mayo Clinic Rochester MN
  • Footnotes
    Commercial Relationships   Y. Siddiqui, None; D.O. Hodge, None; J.D. Cameron, None; D.H. Johnson, None. Grant Identification: Research for the Prevention of Blindness
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 285. doi:
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    • Get Citation

      Y Siddiqui, DO Hodge, JD Cameron, DH Johnson; What Is the Risk of Developing Pigmentary gGaucoma from Pigment Dispersion Syndrome? . Invest. Ophthalmol. Vis. Sci. 2002;43(13):285.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To determine the probability of converting to pigmentary glaucoma (PG) from pigment dispersion syndrome (PDS). Methods: Retrospective population-based study of all newly diagnosed cases of PDS and PG from 1976-1999 in Olmsted County, MN. Criteria for PDS were 2 of 3 signs: iris TI defects, Krukenberg spindles, heavy TM pigment. Criteria for PG were: PDS and 2 of 3 findings: IOP≷21 mmHg, disc damage, visual field loss. Kaplan-Meier survival curves were used to determine the probability of conversion to PG. Results: 119 patients were newly diagnosed with PDS over the 23 year period. Of these, 31 developed PG or PDS with elevated IOP requiring therapy. The probability of converting to PG was 13% at 5 years and 23% at 15 years. An additional 26 patients were found to have pigmentary glaucoma without a previous diagnosis of PDS during this period. Mean age at diagnosis of PDS was 41 years, PG was 44 years. 57% of PDS patients were male, 87% of PG patients were male. Conclusion: The risk of developing PG from PDS is 13% at 5 years and 23% at 15 years.

Keywords: 354 clinical (human) or epidemiologic studies: prevalence/incidence • 355 clinical (human) or epidemiologic studies: risk factor assessment 
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