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C Bisantis, S Piermarocchi, S Vujosevic, M Sartore, F Bisantis, M Dorigo, E Midena; Arterio-Venous Transit Time in the Superficial Layer of the Optic Nerve Head: A New Parameter of Glaucomatous Damage . Invest. Ophthalmol. Vis. Sci. 2002;43(13):334.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose:To evaluate arterio-venous transit time (AVTT) of the superficial layer of the optic nerve head (ONH) in primary open angle glaucoma (POAG). Methods:Circulation times of the superficial layer of the ONH were quantified - in 35 POAG and 35 age-matvhed controls - using an objective, electronic guided examination of a high speed dynamic fluorescein angiography. AVTT of the superficial layer of the ONH was compared between groups, and vs ONH morphology and visual field defects. Results: AVTT of the superficial layer of the ONH was significantly: higher in POAG patients vs controls ( 2.28 vs 1.29 sec; p< .001), and related to ONH morphology and field defects. Conclusion: AVTT of the superficial layer of the ONH may be exactly quantified and may represent a new, objective parameter of glaucomatous damage.
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