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NG Ziakas, K Boboridis, E Nakos, N Georgiadis, NT Stangos; Does The Use Of Trypan Blye During Phacoemulsification Affect The Intraocular Pressure? . Invest. Ophthalmol. Vis. Sci. 2002;43(13):372.
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Purpose:To evaluate the effect of trypan blue on intraocular pressure (IOP) after small incision cataract surgery. Methods:This prospective randomized study comprised 30 eyes of 15 patients with bilateral, dense, age related cataract. Patients with glaucoma or exfoliation syndrome were excluded. The patients were randomly assigned to receive trypan blue during cataract surgery for enhancing capsulorrhexis in one of their eyes, while in their second eye trypan blue was not used. Cataract surgery was performed in an identical fashion in both eyes, with a sutureless posterior limbal incision, phacoemulsification and implantation of a foldable intraocular lens. The same viscoelastic (sodium hyaluronate) was used in all cases and was thoroughly aspirated at the end of the procedure. All patients received a single dose of 250mg acetazolamide 8 hours after surgery. No other antiglaucomatous agent was used during surgery or postoperatively. The IOP was measured preoperatively, and at 24 hours, one week, one month and three months postoperatively. Results:IOP values were similar in both groups at all four postoperative measurements. There was no statistically significant difference in postoperative IOP measurements between the eyes that trypan blue was used and the control eyes. Conclusion:The use of trypan blue during small incision cataract surgery does not have any effects on IOP at the immediate and early postoperative period.
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