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EM Candal, BM DeBroff; The Use Of Staar Collamer IOLS In Uveitic Patients . Invest. Ophthalmol. Vis. Sci. 2002;43(13):416.
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Purpose: To compare post-operative inflammatory response of patients with and without a history of chronic anterior uveitis that underwent routine cataract extraction and had implantation of a Staar collamer posterior chamber intraocular lens. Method: A retrospective chart review was performed of patients that underwent routine cataract extraction at the Yale Eye Center between the months of December 2000 and October 2001. Patients that underwent insertion of Staar collamer posterior chamber intraocular lenses and had a history of chronic anterior uveitis were identified. Anterior chamber inflammatory response was measured using the National Eye Institute Grading Scheme of Anterior Segment Inflammatory Cells: trace: 1-5 cells per high power field; 1+: 6-15; 2+:16-25; 3+: 26-50; 4+: ≷50. Results: We reviewed seventy-seven patients with a total of eighty-five eyes that underwent cataract extraction and had a Staar collamer IOL placed in the capsular bag. Of the total patients included, 3.9% (three eyes) had a pre-operative history of chronic anterior uveitis. Post-operative anterior segment inflammatory response was measured in the uveitic and non-uveitic group at an interval of four weeks. Patients that had a pre-operative history of anterior uveitis had a significantly greater post-operative inflammatory response compared to the non-uveitic subjects (T test: p=0.0067). Conclusion: Patients with a history of chronic uveitis were found to have a more pronounced inflammatory response than patients without a history of uveitis. Newer style and material implants such as the Staar collamer IOL have been developed to be more biocompatible and potentially diminish the inflammatory response. Even with implantation of a Staar collamer IOL and the same technique of minimally invasive surgery, uveitic patients were found to exhibit a more intense post-operative inflammation as compared with non-uveitic patients.
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